1. “In silico” and experimental study of mammalian genome organization and evolution. Understanding how mammalian genomes have been reshuffled during evolution is fundamental to the dynamics of mammalian genome composition, evolutionary relationships between species and, in the long run, speciation, providing insights to how biodiversity originates and is maintained. It is our goal to provide a unified and encompassing view of how genomes are organized and regulated in mammalian cells.
2. Meiotic recombination in mammals. Meiosis is a specialized cell division by which haploid gametes (containing a single copy of each chromosome) are generated. Is in this context where the research activity of the group is focused: described the basis of meiotic recombination in different mammalian species and related this process with evolutionary mechanisms.
3. The role of telomeres in mammalian meiosis. Telomeres play an important role in meiosis, since they bind chromosomes together throughout prophase I by means of the bouquet formation. Preservation of telomere’s structure through specific mechanisms is essential for the appropriate development of meiosis.
4. The CRYO-ZOO: A cell line repository from the Barcelona ZOO collection. A storage facility in which genetic material from endangered species are gathered are scarce world-wide and almost inexistence our country. The CRYO-ZOO is a initiative/collaborative project between the Universitat Autònoma de Barcelona and the Barcelona Zoo, which has as a main goal the creation of a cell line repository from endangered animals from the Barcelona ZOO collection available to the research community.