Development of a new method for the renal calculi diagnosis

Researchers from Centre Grup de Tècniques de Separació en Química, directed by Professor Manuel Valiente and Ass. Prof. Montserrat López Mesas, have developed a new method more reliable, cost effective and fast than the current ones, for the diagnosis of the renal calculi formation by the urine analysis. The new method combines capillary electrophoresis to determine simultaneously four urine substances (oxalate, citrate, uric acid and creatinine) with inductively coupled plasma mass spectrometry to determine fitate.

Scientific have also applied new techniques for the analysis of the composition of either the ejected calculi with urine or the calculi extracted by surgery. Thus, the information obtained leads to determine the origin as well as the process of formation of the calculi and, for the urologist it is a more useful information than the obtained by conventional infrared analysis.

The whole developed techniques will help the urologist in recommending to the patients more concrete actions (diet, take inhibition supplements like fitate or physical activity habits) for the prevention of the future formation of calculi.

The new analysis method is already being carried out in an experimental way with patients from Institut USP-Dexeus (centre that has collaborated with the research) and Hospital de Bellvitge. The Universitat de les Illes Balears has also collaborated with the study.














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