Virtual Clinical Trials: A tool for the Study of Transmission of Nosocomial Infections

TitleVirtual Clinical Trials: A tool for the Study of Transmission of Nosocomial Infections
Publication TypeJournal Article
Year of Publication2017
AuthorsJaramillo, C, Rexachs, D, Epelde, F, Luque, E
JournalProcedia Computer Science
Volume108
Pagination109 - 118
ISSN1877-0509
KeywordsNosocomial Infection
Abstract

A clinical trial is a study designed to demonstrate the efficacy and safety of a drug, procedure, medical device, or diagnostic test. Since clinical trials involve research in humans, they must be carefully designed and must comply strictly with a set of ethical conditions. Logistical disadvantages, ethical constraints, costs and high execution times could have a negative impact on the execution of the clinical trial. This article proposes the use of a simulation tool, the MRSA-T-Simulator, to design and perform “virtual clinical trials” for the purpose of studying \{MRSA\} contact transmission among hospitalized patients. The main advantage of the simulator is its flexibility when it comes to configuring the patient population, healthcare staff and the simulation environment.

URLhttp://www.sciencedirect.com/science/article/pii/S1877050917308736
DOI10.1016/j.procs.2017.05.245
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